The nearly 90-minute debut episode of The Last of Us concludes with Joel (Pascal), Ellie (Ramsey) and Tess (Anna Torv) exiting the FEDRA-controlled Boston quarantine zone, only to be stopped by the guard, who was seen buying drugs earlier in the episode. As the guard checks her infection status outside the zone wall, Ellie lunges at him, forcing Joel to savagely beat him. Moments later, it is revealed that Ellie is infected, although she suggests she is immune to the Cordyceps virus since she was bitten weeks ago. When other guards arrive, the trio decide to run to the ruined and unguarded city.
The episode then switches to Joel’s lair where his radio starts playing Depeche Mode’s “Never Let Me Down Again,” which concludes the episode. “Never Let Me Down Again” was released as a single for Depeche Mode’s sixth album Music for the Masses in 1987. The Grammy-nominated English new wave band were prominent in the ’80s and were responsible for seminal tracks like ‘Enjoy the Silence’ and ‘Personal Jesus’. On first listen, “Never Let Me Down Again” appears to be a tongue-in-cheek and upbeat track that ends the episode on a relatively poignant note. If you dig deeper, it becomes clear that the Depeche Mode song is an integral part of the plot and offers clues as to how Joel and Ellie’s relationship might develop.