In the book The Big Bang Theory: The Definitive, Inside Story of the Epic Hit Series by Jessica Radloff, co-creator Bill Prady discussed how the seed bank scene at the beginning of the show’s pilot had to be eliminated for American Airlines flights . Instead, they filmed an introduction by Johnny Galecki and Jim Parsons, in which Galecki explains, “We won’t be able to show you the first scene because it’s a bit grown up and we don’t know who’s watching over your shoulder. We had a discussion with American Airlines and decided not to show it. But the story works pretty well without that scene, so let’s start with the second scene.” To fill in the time, Parsons then suggests spending a few minutes explaining how planes fly, to which Galecki replies that that nobody wants to hear.
“The Big Bang Theory” continued to have a positive relationship with the airline. In 2011, Kaley Cuoco appeared in a series of public announcements encouraging customers to donate their AAdvantage miles to American Airlines’ Miles for Kids in Need program, which provides air travel for children who are involved in organizations such as Cystic Fibrosis Foundation, the International Hospital, for Children and Miracle Flights (through American Airlines).