In the lore of the Marvel Cinematic Universe, the people of Wakanda worship Bast, the panther goddess of Egypt. Although Bast’s cultural significance wasn’t explored much in the Black Panther films, it was mentioned in other projects such as Thor: Love and Thunder. However, in the comics there is another entity of Wakanda mythology: Sekhmet. T’Challa himself references both goddesses in his debut in Captain America: Civil War, explaining how Bast and Sekhmet welcome the dead to the afterlife.
In the comics, Bast and Sekhmet’s relationship is much more complicated. Sekhmet originated as Hathor, the daughter of Ra, who was transformed into the lion goddess to punish humanity for its disobedience to the ninth. A sibling of Bast, Sekhmet is considered a fringe cult god, while the majority of Wakanda worship Bast. Subsequently, Sekhmet the lion god sought the power of the panther god and brought it into conflict with the Black Panther himself.
The religion of Wakanda would be an interesting area to explore in a future Black Panther movie, as the previous two were mostly about politics and war. In addition, the MCU has already established Egyptian mythology with the Disney+ series “Moon Knight” with the gods Khonshu, Ammit, Osiris and Tawaret. Perhaps the threat of Sekhmet in Wakanda could bring Marc Spector into the fray in a future Black Panther movie, in which Moon Knight and Shuri team up to stop a renegade Egyptian deity.